Benfotiamine (S-benzoylthiamine-O-monophosphate) is a synthetic, lipid-soluble thiamine derivative. Chemical structure of Benfotiamine Formula: C₁₉H₂₃N₄O₆PS Exact mass: ~470.45 g/mol IUPAC: S-benzoylthiamine O-monophosphate The benzoyl group is the key — this blocks water-loving ionic sites → this is why Benfotiamine is fat-soluble (standard thiamine is…
Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic, fat-soluble, S-acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in the late 1950s in…
Benfotiamine is a synthetic, fat-soluble form of Vitamin B1 (Thiamine) that is used mainly to support nerves + lower “AGEs” (advanced glycation end products). This is general information only — not personal medical advice. If you’re on medications (especially diabetes…
Benfotiamine is basically a synthetic fat-soluble derivative of vitamin B1 (thiamine). To be more precise: Parent / basic ingredient: → Thiamine (Vitamin B1) Benfotiamine is chemically: So the core backbone is thiamine, but modified with a benzoate (benzoyl) group and…
Benfotiamine = a synthetic lipid-soluble derivative of thiamine (vitamin B1). Different from regular thiamine because it gets into cells more efficiently and more into the “transketolase pathway” → less harmful AGEs. Main evidence-based application zones Application Why it’s relevant Human…
Benfotiamine supplementation improves cognitive function, reduces oxidative stress, and enhances nerve health, positioning it as a potential therapy for neurodegenerative diseases. Here’s a clear comparison between Benfotiamine and Thiamine (Vitamin B1), highlighting their differences, similarities, and uses: Feature Thiamine (Vitamin B1)…
What Benfotiamine is (quick) Benfotiamine = a fat-soluble derivative of vitamin B1 (thiamine). Because it is fat-soluble, it enters cells more efficiently than regular thiamine. The main researched benefits 1) ↓ AGE formation (Advanced Glycation End-products) This is its strongest…
Benfotiamine is a synthetic, fat-soluble derivative of vitamin B1 (thiamine). Because it’s fat-soluble, the body absorbs it much more efficiently than the common water-soluble thiamine salts (like thiamine hydrochloride). So you can get much higher thiamine levels into tissues using…
5-Deazaflavin is a synthetic analogue of flavin mononucleotide (FMN), where the nitrogen at the 5-position of the isoalloxazine ring replaces the carbon in the original flavin structure. Its synthesis typically involves modifying the core structure of the flavin ring system…