Calcium Hopantenate Hemihydrate
Calcium Hopantenate Hemihydrate is a calcium salt of Hopantenic Acid, which is a derivative of pantothenic acid (vitamin B5).
Description
| Product name | Calcium Hopantenate Hemihydrate |
| Molecular Formula | C20H38CaN2O11 |
| Other name | Calcium (R)-4-(2,4-dihydroxy-3,3-dimethylbutanamid |
| Assay | 98% HPLC |
| Sample | 10g |
| Delivery time | Within 3 working days after payment |
| Usage | Dietary Supplements, Functional Foods, Animal Nutrition |
| Certificates | ISO9001/ISO22000 |
Calcium hopantenate hemihydrate, or HOPA or hopantenic acid calcium salt, functions through a complex mechanism that bridges calcium signalling and neurotransmitter systems in the central nervous system. As a modified form of pantothenic acid (vitamin B5), it combines the properties of both calcium supplementation and nootropic effects.
How to Produce Calcium Hopantenate Hemihydrate Powder?
Raw Material Selection: High-purity hopantenic acid and calcium carbonate/hydroxide sourced. Materials meet pharmaceutical specifications (>98% purity) with testing for impurities, moisture, and heavy metals.
Initial Reaction Setup: The neutralization reaction combines hopantenic acid with a calcium source in purified water at 20-25°C. pH monitoring is throughout.
Reaction Control: The mixture is stirred until complete neutralization is achieved (2-3 hours). Temperature and pH are controlled for optimal salt formation.
Salt Formation: Calcium hopantenate formation monitored under precise conditions. Hydration level controlled for hemihydrate formation.
Product Isolation: Filtration removes undissolved particles. Solution concentrated under controlled conditions. Purification Process: Crystallization with controlled humidity for hemihydrate form. Multiple recrystallization steps ensure purity.
Final Processing: Vacuum dry at 35-40°C until the specified water content (2.5-3.0%) is reached. Milling achieves uniform particle size.
Quality Analysis: Testing includes calcium, HPLC (>98%), water content, structure confirmation, physical parameters, and stability studies.
Test Report
