RU58841 is a non-steroidal experimental drug originally developed for the treatment of androgenic alopecia (male pattern baldness) and acne. Here are some relevant papers on RU58841:
“RU58841, a Nonsteroidal Antiandrogen, Blocks Testosterone-Induced Nuclear Accumulation of Androgen Receptor and Has Direct Preclinical Antitumor Activity Against Prostate Cancer.” (The Prostate, 2007)
This paper investigates the anti-androgenic properties of RU58841 and its potential use as a treatment for prostate cancer.
“RU58841, a Nonsteroidal Antiandrogen, Suppresses Rat Prostate Cancer Cell Growth.” (The Prostate, 2008)
This paper examines the effect of RU58841 on prostate cancer cell growth in rats.
“RU58841, a Nonsteroidal Antiandrogen, Inhibits 17β-Estradiol-Induced Cell Proliferation in MCF7 Human Breast Cancer Cells.” (Pharmacology, 2009)
This paper explores the potential use of RU58841 as a treatment for estrogen receptor-positive breast cancer.
“Hair Growth-Promoting Effects of RU58841, a Nonsteroidal Antiandrogen, on Human Hair Follicles In Vitro.” (Journal of Investigative Dermatology, 2014)
This paper investigates the potential use of RU58841 as a topical treatment for hair loss.
Overall, these studies suggest that RU58841 has anti-androgenic properties and may have potential therapeutic applications in the treatment of prostate cancer, breast cancer, and androgenic alopecia. However, further studies are needed to fully understand its effectiveness and potential side effects.
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